SUBMIT MANUSCRIPT

Donnish Journal of Microbiology and Biotechnology Research

December 2016 Vol. 3(3), pp. 013-020

ISSN: 2984-8679

Copyright 2016 Donnish Journals




Original Research Paper


Virulence Factors of Proteus Species Causing Catheter-Associated Urinary Tract Infection


Basant Mostafa Gabr1*, Wesam Hatem Amer1, Moustafa Sadek Al Rafaey1 and Osama Mohamed Abo Farha2

1Medical Microbiology and Immunology Department, Faculty of Medicine, Tanta University, Egypt.
2Urology Department, Faculty of Medicine, Tanta University, Egypt.

Corresponding Author's Email: posygabr@gmail.com

Accepted 20th November, 2016.



Abstract


One of the most common hospital-acquired infections (HAIs) is catheter-associated urinary tract infection (CAUTI). Proteus species (spp) are the primary infectious agent in patients with long-term indwelling urinary catheters. We aim to study some virulence factors of Proteus spp isolated from CAUTIs; three types of motility: swarming (SW), swimming (SM) and twitching (TW), urease production, biofilm formation and swarming over three different materials of urinary catheters (latex, silicon and silicon coated latex), also, Proteus isolates were tested for their sensitivity to different classes of antibiotics by disc diffusion method. This study was carried on 110 urine samples from CAUTI cases. Proteus isolates were (10/110 isolates, 12.5%). All of them were urease producers, strong biofilm former and had the ability to twitch, swim and swarm all over the plates except one strain. Four strains could bridge over latex catheters while two strains could bridge silicon catheters and silicon coated latex catheters. Seven strains were multidrug resistant (MDR) and two strains were extremely drug resistant (XDR) while only one strain was sensitive, so Proteus isolates from CAUTI are very virulent, so insert urinary catheter only if indicated and if you suspect long duration, use silicon better than latex.

Keywords: CAUTIs, Proteus, virulence factors, Catheter, Urinary tract infection.

Read: [Full Text - PDF]


Cite This Article:

Basant Mostafa Gabr, Wesam Hatem Amer, Moustafa Sadek Al Rafaey and Osama Mohamed Abo Farha. Virulence Factors of Proteus Species Causing Catheter-Associated Urinary Tract Infection. Donnish Journal of Microbiology and Biotechnology Research 3(3) 2016 pp. 013-020.


© 2016 - Donnish Journals | Terms | Privacy policy |