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Donnish Journal of Medical Laboratory and Diagnosis

June 2016 Vol. 2(1), pp. 001-004

Copyright 2016 Donnish Journals




Original Research Paper


Serotypes and Antibiotic Susceptibility of Streptococcus pneumoniae Isolated from Adults with Lower Respiratory Tract Infection in Jos, Nigeria


Okolo M.O1*, Chuhwak E.K2, Emanghe U.E3, Onyedibe K.I1, Banwat E.B1 and Egah D.Z1

1Department of Medical Microbiology and Parasitology, Jos University Teaching Hospital, Jos, Plateau State, Nigeria.
2Department of Medicine, Jos University Teaching Hospital, Jos, Plateau State, Nigeria.
3Department of Medical Microbiology and Parasitology, University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria.

Corresponding Author's Email: okolomarkojogba2b@yahoo.com

Accepted 13th August, 2015.



Abstract


Background: Streptococcus pneumoniae causing lower respiratory tract infection remains a global challenge, particularly when it involves drug resistant isolates. It is a cause of morbidity and mortality in developing countries including Nigeria. Several studies documented the prevalence, serologic and molecular types, antibiotic susceptibility patterns; as well as the herd effect following vaccination. This study thus determined the prevalence of the Heptavalent vaccine serotype of Streptococcus pneumoniae in adult patients and the antibiotic susceptibility pattern. Methods: A cross sectional study involving 91 adult patients with clinical features of lower respiratory tract infection were recruited for this study. Serologic typing as well as antibiotic susceptibility testing were carried out on the Streptococcus pneumoniae isolates. Results: Four (4.4%) of the 91 patients had Streptococcus pneumoniae isolated from their clinical samples. Only one (14.3%) of the heptavalent vaccine serotype (serotype 23F) was found. All the four Pneumococci were susceptible to Ceftriaxone, Levofloxacine, Trimethoprim- sulfamethoxazole and Amoxicillin-clavulanic acid but varying susceptibility to Erythromycin and Tetracycline. Conclusion: Heptavalent vaccine serotype of Streptococcus pneumoniae causes infection in adults. Early detection and appropriate antibiotic susceptibility will enhance proper management of patient. Vaccination of children will reduce infection due to the vaccine serotypes in adult population.

Keywords: Streptococcus pneumoniae, Heptavalent vaccine, Antibiotics, Serology.

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Cite This Article:

Okolo M.O, Chuhwak E.K, Emanghe U.E, Onyedibe K.I, Banwat E.B and Egah D.Z. Serotypes and Antibiotic Susceptibility of Streptococcus pneumoniae Isolated from Adults with Lower Respiratory Tract Infection in Jos, Nigeria. Donnish Journal of Medical Laboratory and Diagnosis 2(1) 2016 pp. 001-004.


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